The chord sequence rarely changes throughout the song, the verse and pre-chorus melodies are highly similar, and the 'whoa-ohs' and chorus sections are virtually identical every time. The song is a natural fusion of multiple sub-genres, including Rock, Pop and Dubstep, all of which are prominent in the charts, but 'Radioactive' is made particularly memorable by its simple and repetitious melody.
'Radioactive' has made the Top-10 in 12 countries and it's no accident: there are several songwriting techniques present that make this a surefire hit.